Searchable abstracts of presentations at key conferences in endocrinology

ea0086p50 | Metabolism, Obesity and Diabetes | SFEBES2022

Single-nucleus RNA sequencing identifies wide-ranging changes in gene expression in mouse nodose ganglia cell populations in response to fasting

Cheng Sijing , Dowsett Georgina , Lam Brian , Norton Mariana , Roberts Anna , Phuah Phyllis , Yeo Giles , Murphy Kevin

Obesity is a leading global health concern. The gut-brain axis is critical to appetite regulation. The vagus nerve represents the major neural pathway between the gastrointestinal tract and the central nervous system, capable of rapidly communicating information about the nutrient content from different regions of the gastrointestinal tract, directly via nutrient receptors expressed on vagal afferents and indirectly by responding to gut hormones and enteric nervous system sign...